Neuroimaging
Quantitative MRI methods for neuroscience studies, including AI-enabled stratification.
Bioxydyn is experienced in the deployment of quantitative MRI methods for neuroscience in conditions including multiple sclerosis, neurodevelopmental conditions, dementia, and neuro-oncology. Our collaboration with Queen Square Analytics enables advanced AI methods for patient stratification with a focus on multiple sclerosis and Alzheimer's disease.
Bioxydyn provides commonly used techniques such as atrophy measurements and diffusion MRI measurements. We also provide more complex quantitative methods, including dynamic contrast-enhanced MRI (DCE-MRI) measurements of subtle blood-brain barrier dysfunction, arterial spin labelling (ASL), MR spectroscopy, and relaxometry. These measurements can be used to interrogate physiological phenomena, metabolism, drug effects, and mechanism of action in a wide range of neurological conditions.
Our neuroimaging workflows combine protocol design, site qualification, quality control, and audited analysis to deliver repeatable biomarkers across sites and scanners. The result is a defensible dataset that supports confident decisions in neurological development programs.